I'm currently following a selected group of accounts and they are enough to keep me up-to-date. If something BIG happens outside of these accounts then it's almost always conveyed via RTs. I also follow some lists
That brings up part of the heart of the question. I follow lots of different things in real life. Martial Arts, exercise with kettlebells, infosec, and a few other geek like things. So I figured breaking up into different accounts would keep the "fluff" down.
I'm still working on the lists. one thing I noted, My doesn't always catch the Re-tweets.
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