I've only got limited experience as I've only used one of the products that you mention, and only from an end-user perspective. My employer recently rolled out CheckPoint PointSec, and I managed to get it to hose my laptop within a week. Hard-drive would not boot past the PointSec login, obviously HDD is encrypted, so recovering data was not possible. Thank goodness for good backup policies.
It seems the system didn't like being booted from a USB stick into BackTrack (disclaimr: may not have been the pen drive, however ran Windows [I know...], booted to Backtrack, back to Windows, dead box)
However, with the exception of my box, the system was successfully rolled out to many users without issue. Buyer beware, in this case backups and system restores covered my a$$.