I think any antivirus will do the main problem with AV is end user don't keep it up to date.

realy do you like eset

Vipre is good

I have avira, it's not a bad one. At work they got Symantec, it's not as bad as i thought 

Play around with msfvenom/encoding and test them out with MSF payloads yourself too.  Big names can be bypassed too.  The only ones I can say stands out are AVG and Kaspersky.  They usually caught the files I created in Metasploit. 

All antivirus sucks   Some just suck less.

I have warmed up to Symantec's Endpoint Protection.  If properly configured (AV, Network Threat Protection and Proactive Threat Protection enabled) it can hold up pretty well.  It also has the ability to implement application and device whitelisting/blacklisting.  That is where much of the AV bypassing payloads can be prevented.  I do like ESET as well, at least at home.  It does a pretty good job catching some things.  Also for home MS Security Essentials was surprisingly good at detecting an infected website download that ESET and AVG missed.

For Enterprise clients I will stick with SEP, for its central management features.  I have not used ESET or Kaspersky in that role, yet.

AV software is only as good as its configuration.  Just like most tools, nothing out-of-the-box will block everything.  Adjustments need to be made to cater to your environment.

Microsoft Security Essentials?  Well for a free home AV it isn't horrible and if I am running Windows I'd much rather rely on Microsoft to know its systems better than a 3rd party in order to protect them.  I usually toss it on my testing machines just because it is free.  They do have an enterprise level AV - Forefront (or whatever it is being called now) which I have yet to use.

Norton Home security suite is just bloatwear in my opninion.