I had trouble landing job interviews until I started writing my resume and cover letter for the job I was applying for.  I had recently graduated college and was sending out the same generic resume.  When I saw the job posting for my current job (Corporate IT for an internet company), I wrote my resume and cover letter for the job posting.  Seriously, it was the first job I wrote the resume for and I got the job.  The same technique also landed me some interview offers, but I had already accepted this position.  I'm hoping to move up to a SysAdmin position soon. 

Another tip for resume is relevant job experience.  A lot of people put down the jobs they have worked that aren't directly related to the job they applying for.  Unless that is the only work experience you have, it doesn't need to be there.

Since you are working towards your BS, you should also be looking for internships.  People have this stigma that internships aren't paid.  My company has SysAdmin, DBA, and Web production internships; all are paid.  I have also seen several interns get promoted to full-time employees.  Internships get your foot in the door, get you experience, and build your contacts/resume.  If possible, you might want to visit your school's career center or chat up advisors/professors about an internships they might know of. 

Another thing you could do call/email people around you who are working in a field you are interested in and ask them if you can ask them a few questions about what they do.  This is reverse interviewing.  Make sure you have planned out what questions you would like to ask, and it gets you some face time with people in the field.  You do this in hopes that when a position opens up they are aware of, they hopefully will give you a heads up or ask for your resume. 

I also forgot to add: Welcome to EH Pacergold!

Lack of experience is certainly frustrating when you're looking for a job. I'm in a similar position and all the job postings I see want at minimum 5+ years experience.

That being said, I've applied for these positions anyway and often gotten interviews out of it.

Additionally, it's possible that the job was posted publicly but they promoted someone from within to that position, which could lead to a more entry-level position being available, they may contact you for that position instead.

Good luck!